Description
Product Characteristics:
Aliases: PABP-interacting protein 2 antibody, PAIP-2 antibody, PAIP2 antibody, PAIP2_HUMAN antibody, poly(A) binding protein interacting protein 2 antibody, Poly(A)-binding protein-interacting protein 2 antibody, Polyadenylate-binding protein-interacting protein 2 antibody
Target Information: Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization (By similarity)